The effect and mechanism of IL-37d on neutrophil recruitment in the early stage of tumor metastasis in the lungs
Our study represents the first investigation into the role of IL-37d in inhibiting tumor metastasis during the early stages by suppressing S100A8/9 and MMP9 expression in lung tissue, thereby reducing neutrophil recruitment and spontaneous migration from the bone marrow.
Authors
- Yetong Guan (ORCID: https://orcid.org/0000-0002-9665-8303)
- Chang Gao
- Yan Guo (ORCID: https://orcid.org/0000-0002-0267-7328)
- Meifang Wang
- Lining Zhang
Institutions
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2024-11-29
- DOI
- https://doi.org/10.1007/s12672-024-01608-7
- Citations
- 4
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.96
Funders
- National Natural Science Foundation of China