Extrinsic electric field modulates neuronal development and increases photoreceptor population in retinal organoids
These findings highlight the significant impact of extrinsic electrical fields on early retinal development and suggest that optimizing electrical field parameters could effectively address certain limitations in retinal organoid technology, potentially reducing the reliance on chemicals and small molecules.
Authors
- Ege Iseri (ORCID: https://orcid.org/0000-0001-7440-7258)
- Magdalene J. Seiler (ORCID: https://orcid.org/0000-0002-0869-9923)
- Deepthi S. Rajendran Nair (ORCID: https://orcid.org/0000-0001-8851-5241)
- Biju B. Thomas (ORCID: https://orcid.org/0000-0002-0312-4450)
- Le Tam Phuong Quach (ORCID: https://orcid.org/0000-0002-1182-5003)
- Gianluca Lazzi (ORCID: https://orcid.org/0000-0002-6365-7283)
- Anika Gupta (ORCID: https://orcid.org/0000-0002-3265-5664)
- Tianyuan Wei
Institutions
- University of Southern California (US)
- University of California, Irvine (US)
- Southern California Eye Institute (US)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2024-11-29
- DOI
- https://doi.org/10.3389/fnins.2024.1438903
- Citations
- 1
- Primary Topic
- Neuroscience and Neural Engineering
- Type
- article
- Field-Weighted Citation Impact
- 0.27
Funders
- National Science Foundation
- Research to Prevent Blindness
- Israel National Institute for Health Policy Research