The Unchanging Latency of Transcranial Motor-Evoked Potentials Among Various Age Groups

Background Human growth and development involve significant changes in bodily dimensions, yet motor learning appears to remain stable throughout life. This study investigates whether adjustments in motor velocity take place as individuals age by examining the latency of transcranial motor-evoked potentials (TcMEPs) across different age groups. Methods Data were collected from 100 patients who underwent surgery with intraoperative neuromonitoring at the All India Institute of Medical Sciences, New Delhi, between January 1, 2019, and January 1, 2020. TcMEP recordings were analyzed for 7 commonly monitored muscles across 7 distinct age groups: under 10 years, 10-19 years, 20-29 years, 30-39 years, 40-49 years, 50-59 years, and over 60 years. Results The analysis revealed no significant differences in motor-evoked potential (MEP) latency across the age groups, indicating that motor response latency remains stable despite the physical changes that occur with aging. Conclusion These findings enhance our understanding of motor learning, suggesting that motor response latency does not necessitate changes with age, highlighting the consistency of motor function over the human lifespan.