A case of Ustilago spp. infection identified by whole genome sequencing in a pediatric patient undergoing open-chest extracorporeal membrane oxygenation

To the best of our knowledge, we presented the first case of an Ustilago spp infection in a pediatric patient undergoing ECMO, not identified by standard techniques but only by WGS performed directly on a blood sample in 5 days. Despite the paucity of literature on Ustilago spp infections treatment, therapy adjustments led to the eradication of the pathogen, underscoring the importance of advanced molecular techniques for the correct and timely identification of these microorganisms.

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Journal
International Journal of Infectious Diseases
Published
2024-11-29
DOI
https://doi.org/10.1016/j.ijid.2024.107320
Primary Topic
Plant Disease Resistance and Genetics
Type
article
Field-Weighted Citation Impact
0.00

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article

A case of Ustilago spp. infection identified by whole genome sequencing in a pediatric patient undergoing open-chest extracorporeal membrane oxygenation

Vanessa Fini, Maria del Carmen Pereyra Boza, Marilena Agosta, Manuela Onori et al.
International Journal of Infectious Diseases
Plant Disease Resistance and Genetics
article

A case of Ustilago spp. infection identified by whole genome sequencing in a pediatric patient undergoing open-chest extracorporeal membrane oxygenation

Vanessa Fini, Maria del Carmen Pereyra Boza, Marilena Agosta, Manuela Onori, Renato Cutrera, Venere Cortazzo, Luna Colagrossi, Valeria Fox, Annarita Granaglia, Barbara Lucignano, Gianluca Foglietta, Elisabetta Verrillo, Gianluca Vrenna, Martina Rossitto, Paola Bernaschi, Carlo Federico Perno, Maria Giovanna Paglietti
article en

Abstract

To the best of our knowledge, we presented the first case of an Ustilago spp infection in a pediatric patient undergoing ECMO, not identified by standard techniques but only by WGS performed directly on a blood sample in 5 days. Despite the paucity of literature on Ustilago spp infections treatment, therapy adjustments led to the eradication of the pathogen, underscoring the importance of advanced molecular techniques for the correct and timely identification of these microorganisms.

International Journal of Infectious DiseasesVol. 151
Bambino Gesù Children's Hospital (IT)
Ospedale Pediatrico Bambino Gesù, Ministero della Salute
Openalex Percentile: Top 88%
Plant Disease Resistance and Genetics
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A case of Ustilago spp. infection identified by whole genome sequencing in a pediatric patient undergoing open-chest extracorporeal membrane oxygenation — Vanessa Fini, Maria del Carmen Pereyra Boza, et al. · International Journal of Infectious Diseases (2024) | TGRS Research Map | TGRS