The people behind the papers – Vahid Zadmajid and Daniel Gorelick

Androgens typically act through nuclear androgen receptors, but they can also activate non-genomic signaling through membrane proteins. How androgens can influence development through membrane-associated androgen signaling pathways is not well understood. In a new study, Daniel Gorelick and colleagues conduct a chemical-genetic screen and identify that testosterone acts through GPRC6A, a G-protein-coupled receptor, during zebrafish embryonic development. To find out more about this work, we caught up with first author Vahid Zadmajid and corresponding author Daniel (Dan) Gorelick, Associate Professor at the Baylor College of Medicine.