Ultraviolet-Light-Induced P–H Insertion of α-Halocarbenes
An intriguing P-H insertion of arylhalodiazirines with <i>H</i>-phosphorus oxides under ultraviolet-light irradiation is described. This methodology provides an efficient and straightforward route to the construction of a variety of α<i>-</i>halophosphorus oxides in good yields (≤95%), which represents a unique example of P-H insertion of α<i>-</i>halocarbenes for C-P bond formation. The metal-free protocol features the advantages of mild reaction conditions, high atom economy, and environmental friendliness.
Authors
- Xiu Gu (ORCID: https://orcid.org/0000-0001-6829-4509)
- Jun Rong Jiang (ORCID: https://orcid.org/0000-0002-5542-7592)
- Nan Huang (ORCID: https://orcid.org/0000-0001-6811-0810)
- Chenyu Liu (ORCID: https://orcid.org/0000-0002-9164-6733)
- Min Zhang (ORCID: https://orcid.org/0000-0002-2458-9564)
- Yifei Zhang
Institutions
- Guangxi University (CN)
Publication Details
- Journal
- Organic Letters
- Published
- 2024-11-29
- DOI
- https://doi.org/10.1021/acs.orglett.4c04049
- Citations
- 6
- Primary Topic
- Cyclopropane Reaction Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.50
Funders
- Natural Science Foundation of Guangxi Zhuang Autonomous Region
- National Natural Science Foundation of China