Signatures of lower respiratory tract microbiome in children with severe community-acquired pneumonia using shotgun metagenomic sequencing
This study demonstrated that significantly different microbial community was associated with severity of community-acquired pneumonia requiring intensive care admission. Species-level shotgun metagenomic sequencing facilitates the exploration of potentially pathogenic or protective microbes and shed the light of probiotic development in lower respiratory tract.
Authors
- Ting‐Yu Yen (ORCID: https://orcid.org/0000-0002-1439-9644)
- Luan‐Yin Chang (ORCID: https://orcid.org/0000-0003-2632-1956)
- Chun‐Yi Lu (ORCID: https://orcid.org/0000-0002-5240-2808)
- Feipei Lai (ORCID: https://orcid.org/0000-0001-7147-8122)
- Tzu‐Yu Liu (ORCID: https://orcid.org/0009-0002-1792-5053)
- Chien-Yu Lin (ORCID: https://orcid.org/0000-0003-0118-3112)
- Ni‐Chung Lee (ORCID: https://orcid.org/0000-0002-5011-7499)
- Hsin Wang (ORCID: https://orcid.org/0000-0003-1929-6449)
- Li‐Min Huang (ORCID: https://orcid.org/0000-0002-9291-260X)
- Ming‐Ju Tsai (ORCID: https://orcid.org/0000-0003-3621-3334)
- Kevin Lee (ORCID: https://orcid.org/0000-0001-5416-4826)
- Chien‐Yu Chen (ORCID: https://orcid.org/0000-0002-6940-6389)
- Che Lin (ORCID: https://orcid.org/0000-0002-4986-311X)
- Ching Hsu (ORCID: https://orcid.org/0000-0003-0560-1019)
- Chengliang Wu (ORCID: https://orcid.org/0000-0002-1741-8345)
Institutions
- National Taiwan University (TW)
- National Taiwan University Hospital (TW)
Publication Details
- Journal
- Journal of Microbiology Immunology and Infection
- Published
- 2024-11-29
- DOI
- https://doi.org/10.1016/j.jmii.2024.11.011
- Citations
- 3
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 0.70
Funders
- Ministry of Science and Technology, Taiwan
- National Taiwan University Hospital
- National Taiwan University