A Case Report of an Osteolytic Mass Hiding Behind an Undiagnosed Parathyroid Adenoma
Hyperparathyroidism is a common endocrinopathy classified into three subtypes: primary, secondary, and tertiary. One of the rare symptoms that patients with hyperparathyroidism present is the formation of osteolytic lesions of the jaws. Brown tumors are rare skeletal osteolytic masses of a poorly understood etiology. These tumors are usually caused by a mutation in the CDC73 gene, a tumor suppressor protein gene that translates to parafibromin. Treatment has been reported to range from a conservative parathyroidectomy to resection and reconstruction. We present a case of a female who presented with a facial disfigurement for four months that was hidden under the effect of a parathyroid adenoma. Our aim is to guide the surgeon in the proper detailed management of osteolytic lesions of jaws that are related to parathyroid hyperfunction.
Authors
- Zaid R. Alzoubi
- Mohammed S. Al Olaimat (ORCID: https://orcid.org/0000-0002-9131-3330)
- Fahad S Al Qooz
- Elham M Alsharaiah
- Abdulkarim M. Alqahtani
Institutions
- King Hussein Medical Center (JO)
Publication Details
- Journal
- Cureus
- Published
- 2024-11-29
- DOI
- https://doi.org/10.7759/cureus.74762
- Primary Topic
- Parathyroid Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00