A retrospective analysis of tacrolimus pharmacokinetic in Saudi paediatric patients in early post-liver transplantation period

Tacrolimus is a drug with high intra- and interindividual variability, making dosing challenging in the paediatric liver transplantation population. Prospective studies with more intensive sampling are needed to address the time-dependent changes in clearance, which will aid in establishing the optimal dosing regimens in this population.

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Publication Details

Journal
Pediatrics & Neonatology
Published
2024-11-29
DOI
https://doi.org/10.1016/j.pedneo.2024.11.001
Primary Topic
Renal Transplantation Outcomes and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

A retrospective analysis of tacrolimus pharmacokinetic in Saudi paediatric patients in early post-liver transplantation period

Hala Joharji, Ahmad F. Alghanem, Abeer Alsmari, Nada A. Alsaleh et al.
Pediatrics & Neonatology
Renal Transplantation Outcomes and Treatments
article

A retrospective analysis of tacrolimus pharmacokinetic in Saudi paediatric patients in early post-liver transplantation period

Hala Joharji, Ahmad F. Alghanem, Abeer Alsmari, Nada A. Alsaleh, Abdullah Alsultan, Mohammed Al-Shagrani, F.T. Alhassan, Ahmed A. Albassam, Huda Alenazi, Dieter Broering, Noureldeen Garaween
article en

Abstract

Tacrolimus is a drug with high intra- and interindividual variability, making dosing challenging in the paediatric liver transplantation population. Prospective studies with more intensive sampling are needed to address the time-dependent changes in clearance, which will aid in establishing the optimal dosing regimens in this population.

Pediatrics & NeonatologyVol. 66(4)
Princess Nourah bint Abdulrahman University (SA), Alfaisal University (SA), Prince Sattam Bin Abdulaziz University (SA), King Saud bin Abdulaziz University for Health Sciences (SA), King Faisal Specialist Hospital & Research Centre (SA), King Saud University (SA), King Abdulaziz Medical City (SA)
Princess Nourah Bint Abdulrahman University
Good health and well-being
Openalex Percentile: Top 59%
Renal Transplantation Outcomes and Treatments
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