Tumor budding and lymphovascular invasion as prognostic factors in p16-positive oropharyngeal squamous cell carcinomas
In addition to LVI, we could identify TB as an independent prognostic factor in p16-positive OPSCC in this multicenter study cohort. Thus, evaluating TB along with LVI in a combined scheme for prognostication might help to establish a more personalized treatment regimen for patients with p16-positive OPSCC.
Authors
- Antoniu‐Oreste Gostian (ORCID: https://orcid.org/0000-0002-9448-1882)
- Melanie Boxberg (ORCID: https://orcid.org/0000-0001-5989-7922)
- Lukas Lükewille
- Matthias Balk (ORCID: https://orcid.org/0000-0002-4938-0441)
- Barbara Wollenberg (ORCID: https://orcid.org/0000-0002-3062-459X)
- Maren Lauterbach
- Markus Hoffmann (ORCID: https://orcid.org/0000-0003-4603-7696)
- Markus Wirth (ORCID: https://orcid.org/0000-0001-7240-5363)
- Moritz Jesinghaus (ORCID: https://orcid.org/0000-0002-0018-5661)
- Christoph Röcken (ORCID: https://orcid.org/0000-0002-6989-8002)
- Iordanis Ourailidis (ORCID: https://orcid.org/0000-0001-6783-5617)
- Benedikt Schmidl (ORCID: https://orcid.org/0000-0003-2201-4246)
- Jochen Heß (ORCID: https://orcid.org/0000-0003-3493-1711)
- Heinrich Iro (ORCID: https://orcid.org/0000-0002-7441-2265)
- Sven Perner (ORCID: https://orcid.org/0000-0002-0449-8462)
- Carolin Mogler (ORCID: https://orcid.org/0000-0003-3400-7254)
- Fabian Stögbauer (ORCID: https://orcid.org/0000-0002-8897-5165)
- Cosima C. Hoch (ORCID: https://orcid.org/0000-0002-3875-7389)
- Julika Ribbat‐Idel (ORCID: https://orcid.org/0000-0003-1262-6572)
- Markus Eckstein (ORCID: https://orcid.org/0000-0001-5418-3349)
- Jan Budczies (ORCID: https://orcid.org/0000-0002-6668-5327)
- Verena-Wilbeth Sailer
- Arndt Hartmann
- Karl‐Ludwig Bruchhage
- Christiane Stuhlmann‐Laeisz
Institutions
- Philipps University of Marburg (DE)
- Friedrich-Alexander-Universität Erlangen-Nürnberg (DE)
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- Christian-Albrechts-Universität zu Kiel (DE)
- Universitätsklinikum Erlangen (DE)
- University Hospital Schleswig-Holstein (DE)
- Research Center Borstel - Leibniz Lung Center (DE)
- Bernstein Center for Computational Neuroscience Tübingen (DE)
- Comprehensive Cancer Center Erlangen (DE)
- Technical University of Munich (DE)
- University of Lübeck (DE)
Publication Details
- Journal
- British Journal of Cancer
- Published
- 2024-11-29
- DOI
- https://doi.org/10.1038/s41416-024-02912-3
- Citations
- 3
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.74
Funders
- Technische Universität München
- Deutsche Krebshilfe