[Comparative analysis of audiovestibular testing results in vestibular schwannomas].

<b>Objective:</b>This study aimed to analyze the results of auditory and vestibular function tests in patients with unilateral vestibular schwannoma and explore their association with tumor size. <b>Methods:</b>Clinical data from 81 patients diagnosed with unilateral vestibular schwannoma who underwent pure-tone audiometry(PTA), cervical and ocular vestibular evoked myogenic potentials(c/oVEMP), as well as video head impulse test(vHIT), and subsequently underwent surgical treatment, were retrospectively analyzed. Patients were categorized into groups based on tumor size: small (≤ 15 mm), medium(16-30 mm), and large (>30 mm), determined by the maximum tumor diameter on contrast-enhanced MRI scans. <b>Results:</b>PTA results indicated hearing loss in 73 cases(90.1%); vestibular function tests revealed abnormal rates for the anterior semicircular canal, horizontal semicircular canal, posterior semicircular canal, utricle, and saccule at 29.6%, 77.8%, 54.3%, 90.1%, and 92.6%, respectively. Statistically, no significant differences were found in preoperative hearing test results among patients in different groups(<i>F</i>=0.393, <i>P</i>=0.676). However, significant differences were observed in horizontal semicircular canal gain(<i>r</i>=-0.248, <i>P</i>=0.025), abnormal rates of horizontal semicircular canal catch-up saccades(<i>r</i>=0.507, <i>P</i><0.001), as well as cVEMP(χ²=15.111, <i>P</i>=0.004) and oVEMP thresholds(χ²=18.948, <i>P</i><0.001) across varying tumor size groups. <b>Conclusion:</b>The extent of hearing loss in patients with vestibular schwannoma is not correlated with tumor size, whereas the degree of vestibular dysfunction demonstrates a correlation with tumor size.

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PubMed
Published
2024-12-01
DOI
https://doi.org/10.13201/j.issn.2096-7993.2024.12.005
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1
Primary Topic
Meningioma and schwannoma management
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article
Field-Weighted Citation Impact
0.39
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article

[Comparative analysis of audiovestibular testing results in vestibular schwannomas].

Yanbo Yin, Jiamin Gong, Xiaoling Shi, Weidong Zhao et al.
1 citations
PubMed
Meningioma and schwannoma management
0.39
article

[Comparative analysis of audiovestibular testing results in vestibular schwannomas].

Yanbo Yin, Jiamin Gong, Xiaoling Shi, Weidong Zhao, Yunfeng Wang
article en
1 citations

Abstract

<b>Objective:</b>This study aimed to analyze the results of auditory and vestibular function tests in patients with unilateral vestibular schwannoma and explore their association with tumor size. <b>Methods:</b>Clinical data from 81 patients diagnosed with unilateral vestibular schwannoma who underwent pure-tone audiometry(PTA), cervical and ocular vestibular evoked myogenic potentials(c/oVEMP), as well as video head impulse test(vHIT), and subsequently underwent surgical treatment, were retrospectively analyzed. Patients were categorized into groups based on tumor size: small (≤ 15 mm), medium(16-30 mm), and large (>30 mm), determined by the maximum tumor diameter on contrast-enhanced MRI scans. <b>Results:</b>PTA results indicated hearing loss in 73 cases(90.1%); vestibular function tests revealed abnormal rates for the anterior semicircular canal, horizontal semicircular canal, posterior semicircular canal, utricle, and saccule at 29.6%, 77.8%, 54.3%, 90.1%, and 92.6%, respectively. Statistically, no significant differences were found in preoperative hearing test results among patients in different groups(<i>F</i>=0.393, <i>P</i>=0.676). However, significant differences were observed in horizontal semicircular canal gain(<i>r</i>=-0.248, <i>P</i>=0.025), abnormal rates of horizontal semicircular canal catch-up saccades(<i>r</i>=0.507, <i>P</i><0.001), as well as cVEMP(χ²=15.111, <i>P</i>=0.004) and oVEMP thresholds(χ²=18.948, <i>P</i><0.001) across varying tumor size groups. <b>Conclusion:</b>The extent of hearing loss in patients with vestibular schwannoma is not correlated with tumor size, whereas the degree of vestibular dysfunction demonstrates a correlation with tumor size.

PubMedVol. 38(12)
Eye & ENT Hospital of Fudan University (CN)
Openalex Percentile: Top 32%
Meningioma and schwannoma management
0.39
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