Serum trimethylamine N-oxide and its precursors are associated with the occurrence of mild cognition impairment as well as changes in neurocognitive status
The findings suggest the existence of an optimal concentration range for serum levels of TMAO, betaine, and carnitine that mitigates MCI risk, paving the way for enhanced dietary interventions aimed at preventing and treating MCI.
Authors
- Enmao Cai
- Wenli Ruan
- Ying Lü (ORCID: https://orcid.org/0000-0002-7698-8962)
- Mingfeng Ma
- Ruiheng Peng (ORCID: https://orcid.org/0000-0001-7593-6143)
- Yani Wu (ORCID: https://orcid.org/0009-0006-3664-8791)
- Liqiang Zheng (ORCID: https://orcid.org/0000-0003-0422-9585)
- Yao Zhang (ORCID: https://orcid.org/0000-0001-8878-891X)
- He Bai
- Peiying Tian
- Bin Liang
Institutions
- Shanxi Medical University (CN)
- Shanghai Jiao Tong University (CN)
- Fudan University (CN)
- XinHua Hospital (CN)
- Pudong Medical Center (CN)
- Second Hospital of Shanxi Medical University (CN)
- Shanxi Fenyang Hospital (CN)
- Shanghai Municipal Center For Disease Control Prevention (CN)
- China Medical University (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2024-11-28
- DOI
- https://doi.org/10.3389/fnut.2024.1461942
- Citations
- 3
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- National Natural Science Foundation of China