Impact of switching to a dolutegravir‐based regimen on body weight changes: insights from West African adult HIV cohorts
In West Africa, a 12-month DTG exposure was associated with substantial weight gain, especially in PLHIV previously on EFV and PI-based ARTs. Continuous weight monitoring and metabolic profiling is imperative in HIV cohorts to delineate the long-term cardiometabolic impact of DTG as patients with, or at elevated risk for cardiovascular diseases might benefit from alternative ART regimens.
Authors
- Igho Ofotokun
- Cecile Delille Lahiri (ORCID: https://orcid.org/0000-0002-5605-8266)
- Armel Poda (ORCID: https://orcid.org/0000-0002-7463-9179)
- A. Minga (ORCID: https://orcid.org/0009-0005-7139-2026)
- Oliver Ezechi (ORCID: https://orcid.org/0000-0003-0688-3898)
- Thierry Tiendrebeogo (ORCID: https://orcid.org/0000-0002-9393-9732)
- Didier K. Ekouevi
- Karen Malateste
- Antoine Jaquet
Institutions
- Emory University (US)
- Université de Bordeaux (FR)
- Inserm (FR)
- Nazi Boni University (BF)
- Bordeaux Population Health (FR)
- Institut de Recherche pour le Développement (FR)
- University of Lomé (TG)
- Nigerian Institute of Medical Research (NG)
Publication Details
- Journal
- Journal of the International AIDS Society
- Published
- 2024-11-27
- DOI
- https://doi.org/10.1002/jia2.26371
- Citations
- 9
- Primary Topic
- HIV-related health complications and treatments
- Type
- article
- Field-Weighted Citation Impact
- 6.22
Funders
- National Institute on Alcohol Abuse and Alcoholism
- National Heart, Lung, and Blood Institute
- National Institute on Drug Abuse
- National Cancer Institute
- National Institute of Allergy and Infectious Diseases
- Fogarty International Center
- National Institute of Diabetes and Digestive and Kidney Diseases
- Eunice Kennedy Shriver National Institute of Child Health and Human Development