Yishen paidu pills attenuates 5/6 nephrectomy induced kidney disease via inhibiting the PI3K/AKT/mTOR signaling pathway
The study identified the chemicals of YSPDP and revealed that YSPDP prevented the progression of CKD by inhibiting PI3K/AKT/mTOR signaling in 5/6 SNx rats.
Authors
- Lijun Yao (ORCID: https://orcid.org/0000-0003-2613-0025)
- Saiji Liu
- Chun Zhang (ORCID: https://orcid.org/0000-0003-3565-8024)
- Qian Yuan (ORCID: https://orcid.org/0000-0002-3371-3336)
- Yaru Xie (ORCID: https://orcid.org/0000-0002-9454-0600)
- Yuting Zhu (ORCID: https://orcid.org/0000-0001-7412-7272)
- Yiling Cao (ORCID: https://orcid.org/0009-0000-9138-9135)
Institutions
- Union Hospital (HK)
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-11-28
- DOI
- https://doi.org/10.3389/fphar.2024.1510098
- Citations
- 3
- Primary Topic
- Chronic Kidney Disease and Diabetes
- Type
- article
- Field-Weighted Citation Impact
- 1.02
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China