Network pharmacology, experimental validation and pharmacokinetics integrated strategy to reveal pharmacological mechanism of goutengsan on methamphetamine dependence
GTS treats MA dependence by regulating the MAPK pathway via multiple bioactive ingredients. The network pharmacology, experimental validation and pharmacokinetics integrated strategy is efficient in discovering the key pharmacological mechanism of herbal formulae.
Authors
- Xing-Chen Wang (ORCID: https://orcid.org/0000-0001-5557-4966)
- Chang‐Shun Liu (ORCID: https://orcid.org/0000-0003-2841-1795)
- Chung Yin Kong (ORCID: https://orcid.org/0000-0001-6431-7830)
- Jieyu Li (ORCID: https://orcid.org/0000-0002-9147-3756)
- Hancheng Li (ORCID: https://orcid.org/0000-0002-5963-1494)
- Kelin Chen (ORCID: https://orcid.org/0000-0002-8066-2826)
- Zhixian Mo (ORCID: https://orcid.org/0000-0002-4100-7298)
- Ming Zeng (ORCID: https://orcid.org/0000-0002-1563-2524)
- Jiaxuan Zhang (ORCID: https://orcid.org/0009-0005-1931-2244)
- Yi‐Ling Chen (ORCID: https://orcid.org/0000-0002-9789-2441)
- J. Wu (ORCID: https://orcid.org/0000-0003-4703-0672)
- Yangkai Wu
Institutions
- Zhaoqing University (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-11-28
- DOI
- https://doi.org/10.3389/fphar.2024.1480562
- Citations
- 2
- Primary Topic
- Ginseng Biological Effects and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.47
Funders
- National Natural Science Foundation of China