Advancements in Epstein-Barr virus-associated B-cell lymphomas: molecular mechanisms and targeted therapeutic strategies

<p indent="0mm">EB病毒通过感染B淋巴细胞, 在多种B细胞淋巴瘤的发生和发展中发挥重要作用. 围绕EB病毒的研究不仅能够显著提升对B细胞淋巴瘤的临床诊断与疾病监测水平, 还为阐明其致病机制以及开发精准高效的治疗策略提供关键线索. 本文综述了三类常见的EB病毒相关B细胞淋巴瘤——伯基特淋巴瘤(Burkitt lymphoma)、霍奇金淋巴瘤(Hodgkin lymphoma)和弥漫大B细胞淋巴瘤(diffuse large B cell lymphoma)的研究进展, 重点总结了病毒感染在B细胞淋巴瘤发生和发展中的分子机制, 并系统探讨了靶向EB病毒的治疗策略及其应用前景, 为推动相关疾病的精准医学研究和临床转化提供了重要理论依据和实践指导.

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Publication Details

Journal
Scientia Sinica Vitae
Published
2024-11-28
DOI
https://doi.org/10.1360/ssv-2024-0189
Primary Topic
Viral-associated cancers and disorders
Type
article
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article

Advancements in Epstein-Barr virus-associated B-cell lymphomas: molecular mechanisms and targeted therapeutic strategies

Yiqi Li, Jinxin Bei
2 links
Scientia Sinica Vitae
Viral-associated cancers and disorders
article

Advancements in Epstein-Barr virus-associated B-cell lymphomas: molecular mechanisms and targeted therapeutic strategies

Yiqi Li, Jinxin Bei
article en

Abstract

<p indent="0mm">EB病毒通过感染B淋巴细胞, 在多种B细胞淋巴瘤的发生和发展中发挥重要作用. 围绕EB病毒的研究不仅能够显著提升对B细胞淋巴瘤的临床诊断与疾病监测水平, 还为阐明其致病机制以及开发精准高效的治疗策略提供关键线索. 本文综述了三类常见的EB病毒相关B细胞淋巴瘤——伯基特淋巴瘤(Burkitt lymphoma)、霍奇金淋巴瘤(Hodgkin lymphoma)和弥漫大B细胞淋巴瘤(diffuse large B cell lymphoma)的研究进展, 重点总结了病毒感染在B细胞淋巴瘤发生和发展中的分子机制, 并系统探讨了靶向EB病毒的治疗策略及其应用前景, 为推动相关疾病的精准医学研究和临床转化提供了重要理论依据和实践指导.

Scientia Sinica VitaeVol. 54(12)
Openalex Percentile: Top 62%
Viral-associated cancers and disorders
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Advancements in Epstein-Barr virus-associated B-cell lymphomas: molecular mechanisms and targeted therapeutic strategies — Yiqi Li, Jinxin Bei · Scientia Sinica Vitae (2024) | TGRS Research Map | TGRS