Anticancer Potential of some Plants of Mythological Importance

Background: Cancer is considered one of the leading causes of death internationally, accounting for nearly 10 million deaths in 2020. It was reported that between 30 and 50% of cancers may be prevented by warding off risk factors and imposing existing proof-based prevention techniques. The cancer burden can also be reduced through early detection of cancer and appropriate remedies and care for patients who develop most cancers. Objective: The objective of the research work is to check out the importance of shortlisted medicinal plants of mythological importance in cancer management. Methods: Michelia champaca and Elaeocarpus ganitrus have been obtained from the BBD Group campus and NBRI Garden, Lucknow, and authenticated by CSIR Institute NISCAIR (Raw Material & Herbarium Division), New Delhi. Extraction was performed by use of a warm system known as the Soxhlet extraction method with the utilization of hydroalcoholic solvent, and the plants were further studied for their anticancer activity in various cancer cell lines, including MCF-7, HeLa, and HepG2 cell lines. Results: Phytonutrients are found in both shortlisted plants; Elaeocarpus ganitrus and Michelia champaca are responsible for their medicinal importance. Both medicinal plants have been investigated for anticancer activity, and it was found that both plants have the capacity to reduce the proliferation rate and also induce apoptosis of cancer cells. Conclusion: Phytochemical analysis of Elaeocarpus ganitrus and Michelia champaca (leaves) extracts were found to have alkaloids, flavonoid content material, phenolic compounds, and many others., and exceptional antioxidant properties. Ultimately, Elaeocarpus ganitrus and Michelia champaca have a satisfactory capacity to supply pure antioxidants for livestock, and further relevant research along these lines would be profitable.