Neuroprotective Potential of Tanshinone-IIA in Mitigating Propionic Acidinduced Experimental Autism-like Behavioral and Neurochemical Alterations: Insights into c-JNK and p38MAPK Pathways
Thus, Tan-IIA has a neuroprotective potential by inhibiting the c-JNK and p38MAPK signalling pathways, which reduces the behavioral and neurochemical abnormalities induced by PPA in adult Wistar rats, indicating that current results should be studied further for the diagnosis and treatment of autism.
Authors
- Zuber Khan (ORCID: https://orcid.org/0000-0002-0887-754X)
- Acharan S. Narula
- Sidharth Mehan (ORCID: https://orcid.org/0000-0003-0034-835X)
- Ghanshyam Das Gupta (ORCID: https://orcid.org/0000-0002-5377-1082)
- Kajal Sherawat
- Aarti Tiwari (ORCID: https://orcid.org/0000-0002-8465-5324)
Institutions
- Indo Soviet Friendship College of Pharmacy (IN)
- Punjab Technical University (IN)
Publication Details
- Journal
- Current Molecular Pharmacology
- Published
- 2024-11-28
- DOI
- https://doi.org/10.2174/0118761429326799241121104310
- Citations
- 8
- Primary Topic
- Traditional Chinese Medicine Analysis
- Type
- article
- Field-Weighted Citation Impact
- 5.73