Intratumoral delivery of mRNA encoding the endogenous TLR2/6 agonist UNE-C1 induces immunogenic cell death and enhances antitumor activity
Our results advocate for the intratumoral delivery of UNE-C1 via mRNA therapy as a promising strategy for innovative antitumor treatments.
Authors
- Sang Bum Kim
- Yungyeong Shin
- Uijoo Kim
- Seong-Min Cho (ORCID: https://orcid.org/0000-0001-7497-8747)
- Ji Hun Suh
- Jihye Choi (ORCID: https://orcid.org/0000-0003-2512-2592)
- Ina Yoon (ORCID: https://orcid.org/0000-0001-5307-3754)
- Joohee Park (ORCID: https://orcid.org/0000-0003-3903-8383)
- Hyeong Yun Kim
- Hyuk‐Sang Kwon (ORCID: https://orcid.org/0000-0003-4026-4572)
- Nayoung Kim (ORCID: https://orcid.org/0000-0002-9397-0406)
- Sunghoon Kim (ORCID: https://orcid.org/0000-0002-1645-7473)
- Sunkyo Hwang
- Jeongwon Mun
- Hamin Ban
Institutions
- Yonsei University (KR)
- Sahmyook University (KR)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-11-28
- DOI
- https://doi.org/10.3389/fimmu.2024.1454504
- Citations
- 2
- Primary Topic
- Immune Response and Inflammation
- Type
- article
- Field-Weighted Citation Impact
- 0.48
Funders
- National Research Foundation
- Yonsei University
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea