Research on the effect of LAMP1 in the development and progression of ccRCC and its potential mechanism with LC3C-mediated autophagy
These findings indicate that low expression levels of LAMP1 is associated with poor prognosis in ccRCC. Therefore, LAMP1 emerges as a novel biomarker associated with the diagnosis and prognosis of renal cancer. Furthermore, we have also described the potential mechanism of action of LAMP1 in renal cancer. LAMP1 is a promising target for the treatment of ccRCC.
Authors
- Xiongbao Wang
- Liang Fang (ORCID: https://orcid.org/0000-0003-4502-1756)
- Bing-Shen Wang
- Minghao Han (ORCID: https://orcid.org/0000-0002-2027-328X)
- Yuanwei Zang (ORCID: https://orcid.org/0000-0002-2265-3198)
- Guangxin Zhong
- Juchao Ren
- Lixiang Xiao
Institutions
- Shandong University (CN)
- Beijing Tsinghua Chang Gung Hospital (CN)
- Qilu Hospital of Shandong University (CN)
- Tsinghua University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-11-28
- DOI
- https://doi.org/10.3389/fimmu.2024.1494005
- Citations
- 1
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 0.39
Funders
- Shandong University
- Qilu Hospital of Shandong University
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province