Spectrum of offending drugs and cutaneous adverse drug reactions requiring hospitalisation in a tertiary South African hospital in TB/HIV endemic setting

Typical and atypical presentations of SCAR were represented in this vulnerable South African cohort of predominantly PWH. SJS/TEN was the commonest phenotype, and cotrimoxazole the most frequent offending drug. This data emphasises the need for prospective data collection across a diverse African population for valid SCAR phenotyping and drug causality assessment.

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Publication Details

Journal
Frontiers in Allergy
Published
2024-11-28
DOI
https://doi.org/10.3389/falgy.2024.1481281
Primary Topic
Drug-Induced Adverse Reactions
Type
article
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article

Spectrum of offending drugs and cutaneous adverse drug reactions requiring hospitalisation in a tertiary South African hospital in TB/HIV endemic setting

Bukiwe Thwala, Jonny Peter, Rannakoe Lehloenya, Avumile Mankahla et al.
Frontiers in Allergy
Drug-Induced Adverse Reactions
article

Spectrum of offending drugs and cutaneous adverse drug reactions requiring hospitalisation in a tertiary South African hospital in TB/HIV endemic setting

Bukiwe Thwala, Jonny Peter, Rannakoe Lehloenya, Avumile Mankahla, Martina Lee Porter, Samkele Konyana, Elizabeth Jane Phillips, Nadine Teixeira, L. Pirjol, W. Nkoyane, Fungiwe Gxolo
article en

Abstract

Typical and atypical presentations of SCAR were represented in this vulnerable South African cohort of predominantly PWH. SJS/TEN was the commonest phenotype, and cotrimoxazole the most frequent offending drug. This data emphasises the need for prospective data collection across a diverse African population for valid SCAR phenotyping and drug causality assessment.

Frontiers in AllergyVol. 5
University of Cape Town (ZA), Murdoch University (AU), Groote Schuur Hospital (ZA), Nelson Mandela Academic Hospital (ZA), Vanderbilt University Medical Center (US), Walter Sisulu University (ZA)
Good health and well-being
Openalex Percentile: Top 79%
Drug-Induced Adverse Reactions
DOIOpen Access PDFOpenAlex
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Spectrum of offending drugs and cutaneous adverse drug reactions requiring hospitalisation in a tertiary South African hospital in TB/HIV endemic setting — Bukiwe Thwala, Jonny Peter, et al. · Frontiers in Allergy (2024) | TGRS Research Map | TGRS