Adrenal oncocytoma: a rare presentation of a benign 18F-fluorodeoxyglucose PET avid virilising adrenal tumour

A woman in her 70s presented with features of hyperandrogenism including clitoral enlargement and deepening of her voice. Biochemical investigations revealed raised plasma androgens and urinary androgen metabolites and imaging findings showed a highly F-18 fluorodeoxyglucose (FDG)-PET avid left adrenal tumour initially suspected to be a malignant adrenocortical carcinoma (ACC). She subsequently underwent an uncomplicated laparoscopic adrenalectomy where complete resection of her tumour was achieved. Histopathological analysis demonstrated a benign adrenal oncocytoma with no evidence of malignancy. This case illustrates a rare presentation of a functioning virilising adrenal oncocytoma as a benign mimic of ACC.

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Publication Details

Journal
Nuclear Medicine Communications
Published
2024-11-28
DOI
https://doi.org/10.1097/mnm.0000000000001932
Citations
1
Primary Topic
Adrenal and Paraganglionic Tumors
Type
article
Field-Weighted Citation Impact
0.57
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article

Adrenal oncocytoma: a rare presentation of a benign 18F-fluorodeoxyglucose PET avid virilising adrenal tumour

James W. Crane, Danielle Hyunsook Lee, Koshy Jacob, Dylan Lewis et al.
1 citations
Nuclear Medicine Communications
Adrenal and Paraganglionic Tumors
0.57
article

Adrenal oncocytoma: a rare presentation of a benign 18F-fluorodeoxyglucose PET avid virilising adrenal tumour

James W. Crane, Danielle Hyunsook Lee, Koshy Jacob, Dylan Lewis, David R. Taylor, Simon Aylwin, Saira Reynolds, G Galatà, Matthew Seager, Ben Whitelaw, Jonathan Green, Wen Ng
article en
1 citations

Abstract

A woman in her 70s presented with features of hyperandrogenism including clitoral enlargement and deepening of her voice. Biochemical investigations revealed raised plasma androgens and urinary androgen metabolites and imaging findings showed a highly F-18 fluorodeoxyglucose (FDG)-PET avid left adrenal tumour initially suspected to be a malignant adrenocortical carcinoma (ACC). She subsequently underwent an uncomplicated laparoscopic adrenalectomy where complete resection of her tumour was achieved. Histopathological analysis demonstrated a benign adrenal oncocytoma with no evidence of malignancy. This case illustrates a rare presentation of a functioning virilising adrenal oncocytoma as a benign mimic of ACC.

Nuclear Medicine CommunicationsVol. 46(4)
King's College London (GB), Eastbourne District General Hospital (GB), King's College Hospital NHS Foundation Trust (GB)
Good health and well-being
Openalex Percentile: Top 27%
Adrenal and Paraganglionic Tumors
0.57
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Adrenal oncocytoma: a rare presentation of a benign 18F-fluorodeoxyglucose PET avid virilising adrenal tumour — James W. Crane, Danielle Hyunsook Lee, et al. · Nuclear Medicine Communications (2024) | TGRS Research Map | TGRS