Adenosine deaminase acting on RNA 2 provides neuroprotection by activating Kv1.1 channels in a rat epilepsy model
Our findings confirm that the upregulation of ADAR2 promotes Kv1.1 protein expression, which ultimately reduces neuronal damage in the hippocampus of animals with epilepsy.
Authors
- Pengzhen Wang (ORCID: https://orcid.org/0000-0002-6603-3206)
- Pingping Zhu (ORCID: https://orcid.org/0000-0002-8009-2923)
- Jian Wu (ORCID: https://orcid.org/0000-0002-3394-1507)
- Bo Ning (ORCID: https://orcid.org/0009-0002-3601-7544)
- Wenquan Liu (ORCID: https://orcid.org/0000-0001-6728-9038)
- Wei Yuan (ORCID: https://orcid.org/0009-0001-9812-2297)
Institutions
- Jinan University (CN)
Publication Details
- Journal
- CytoJournal
- Published
- 2024-11-28
- DOI
- https://doi.org/10.25259/cytojournal_53_2024
- Citations
- 3
- Primary Topic
- RNA regulation and disease
- Type
- article
- Field-Weighted Citation Impact
- 0.70