Environment benign synthesis of 5-acyl-4-hydroxypyridin-2(1 <i>H</i> )-one derivatives as antioxidant and <i>α</i> -amylase inhibitors
Compound 4a was found to be promising antioxidant and 4c as a good α-amylase inhibitor. These compounds could pave the way for development of new α-amylase inhibitors with antioxidant capabilities thereby effectively mitigating diabetes mellitus.
Authors
- Vidhi Dhanda (ORCID: https://orcid.org/0009-0006-4854-1772)
- Jayant Sindhu (ORCID: https://orcid.org/0000-0003-0207-0662)
- Anil Duhan (ORCID: https://orcid.org/0000-0001-8087-3677)
- Sarita Sangwan (ORCID: https://orcid.org/0000-0001-8413-1478)
- Neelam R. Yadav (ORCID: https://orcid.org/0000-0002-1068-1044)
- Ravi Kumar (ORCID: https://orcid.org/0000-0001-8146-9799)
Institutions
- Chaudhary Charan Singh Haryana Agricultural University (IN)
Publication Details
- Journal
- Future Medicinal Chemistry
- Published
- 2024-11-28
- DOI
- https://doi.org/10.1080/17568919.2024.2432289
- Primary Topic
- Synthesis and biological activity
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Council of Scientific and Industrial Research, India