Therapeutic Efficacy of Reduced Glutathione in Emergency Treatment of Organophosphorus Pesticide Poisoning and Its Impact on ALT, AST, CRP, and IL-6 Levels

Objective: To analyze the efficacy of reduced glutathione (GSH) in the emergency treatment of patients with organophosphorus pesticide poisoning (AOPP). Methods: A total of 100 AOPP patients admitted to the emergency department between January 2022 and January 2024 were selected and randomly divided into two groups. The observation group (n = 50) received GSH combined with conventional treatment, while the reference group (n = 50) received conventional treatment alone. The overall treatment efficacy, serum indicators, and adverse reaction rates were compared. Results: The observation group exhibited a higher overall treatment efficacy compared to the reference group (P < 0.05). Post-treatment, serum indicator levels in the observation group were lower than those in the reference group, and the adverse reaction rate was also lower in the observation group (P < 0.05). Conclusion: GSH can improve the overall treatment efficacy in AOPP patients, protect liver function, reduce inflammatory responses in the body, and minimize post-treatment adverse effects, thus accelerating recovery and demonstrating significant therapeutic advantages.

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Publication Details

Journal
Journal of Clinical and Nursing Research
Published
2024-11-28
DOI
https://doi.org/10.26689/jcnr.v8i11.8987
Citations
1
Primary Topic
Pesticide Exposure and Toxicity
Type
article
Field-Weighted Citation Impact
0.60
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article

Therapeutic Efficacy of Reduced Glutathione in Emergency Treatment of Organophosphorus Pesticide Poisoning and Its Impact on ALT, AST, CRP, and IL-6 Levels

Yuezhou Wang
1 citations
Journal of Clinical and Nursing Research
Pesticide Exposure and Toxicity
0.60
article

Therapeutic Efficacy of Reduced Glutathione in Emergency Treatment of Organophosphorus Pesticide Poisoning and Its Impact on ALT, AST, CRP, and IL-6 Levels

Yuezhou Wang
article en
1 citations

Abstract

Objective: To analyze the efficacy of reduced glutathione (GSH) in the emergency treatment of patients with organophosphorus pesticide poisoning (AOPP). Methods: A total of 100 AOPP patients admitted to the emergency department between January 2022 and January 2024 were selected and randomly divided into two groups. The observation group (n = 50) received GSH combined with conventional treatment, while the reference group (n = 50) received conventional treatment alone. The overall treatment efficacy, serum indicators, and adverse reaction rates were compared. Results: The observation group exhibited a higher overall treatment efficacy compared to the reference group (P < 0.05). Post-treatment, serum indicator levels in the observation group were lower than those in the reference group, and the adverse reaction rate was also lower in the observation group (P < 0.05). Conclusion: GSH can improve the overall treatment efficacy in AOPP patients, protect liver function, reduce inflammatory responses in the body, and minimize post-treatment adverse effects, thus accelerating recovery and demonstrating significant therapeutic advantages.

Journal of Clinical and Nursing ResearchVol. 8(11)
Lianyungang Oriental Hospital (CN)
Good health and well-being
Openalex Percentile: Top 21%
Pesticide Exposure and Toxicity
0.60
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