Tryptanthrin Down-Regulates Oncostatin M by Targeting GM-CSF-Mediated PI3K-AKT-NF-κB Axis
Therefore, these results reveal for the first time that TRYP inhibits OSM release via the down-regulation of PI3K-AKT-NF-κB axis from neutrophils, presenting its potential as a therapeutic agent for inflammatory responses.
Authors
- Phil-Dong Moon (ORCID: https://orcid.org/0000-0003-2800-1999)
- Seong‐Gyu Ko (ORCID: https://orcid.org/0000-0002-2345-430X)
- Hi‐Joon Park (ORCID: https://orcid.org/0000-0002-0538-2664)
- Na‐Ra Han (ORCID: https://orcid.org/0009-0006-2039-8812)
Institutions
- Kyung Hee University (KR)
Publication Details
- Journal
- Nutrients
- Published
- 2024-11-28
- DOI
- https://doi.org/10.3390/nu16234109
- Citations
- 2
- Primary Topic
- Cytokine Signaling Pathways and Interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.57