Associations of Iron Deficiency with Cardiac Function, Congestion, Exercise Capacity and Prognosis in Heart Failure

In HF outpatients, TSAT <20% is more consistently associated with congestion by ultrasound and poorer functional capacity than other ID definitions, irrespective of LVEF. TSAT <20% and iron ≤13 μmol/L, but not G-ID or ferritin-based ID, predict a worse prognosis in HF outpatients with preserved and reduced LVEF.

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Publication Details

Journal
European Journal of Heart Failure
Published
2024-11-28
DOI
https://doi.org/10.1002/ejhf.3534
Citations
15
Primary Topic
Heart Failure Treatment and Management
Type
article
Field-Weighted Citation Impact
6.03

Funders

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article

Associations of Iron Deficiency with Cardiac Function, Congestion, Exercise Capacity and Prognosis in Heart Failure

Wouter L’Hoyes, John G.F. Cleland, Stefano Masi, G Masini et al.
15 citations
European Journal of Heart Failure
Heart Failure Treatment and Management
6.03
article

Associations of Iron Deficiency with Cardiac Function, Congestion, Exercise Capacity and Prognosis in Heart Failure

Wouter L’Hoyes, John G.F. Cleland, Stefano Masi, G Masini, Jan Verwerft, Luna Gargani, Lavinia Del Punta, Pierpaolo Pellicori, Alessandro Mengozzi, Lieven Herbots, Sarah Hoedemakers, Stefano Taddei, Jan Stassen, Nicola Riccardo Pugliese, Nicolò De Biase, Sara Ferreira, Silvia Armenia, Valerio Fiore
article en
15 citations

Abstract

In HF outpatients, TSAT <20% is more consistently associated with congestion by ultrasound and poorer functional capacity than other ID definitions, irrespective of LVEF. TSAT <20% and iron ≤13 μmol/L, but not G-ID or ferritin-based ID, predict a worse prognosis in HF outpatients with preserved and reduced LVEF.

European Journal of Heart FailureVol. 27(5)
University of Pisa (IT), Jessa Hospital (BE), Equilibrium Research (GB), Azienda Ospedaliera Universitaria Pisana (IT), University of Glasgow (GB), Hasselt University (BE)
Bristol-Myers Squibb, AstraZeneca, European Commission
Good health and well-being
Openalex Percentile: Top 3%
Heart Failure Treatment and Management
6.03
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Associations of Iron Deficiency with Cardiac Function, Congestion, Exercise Capacity and Prognosis in Heart Failure — Wouter L’Hoyes, John G.F. Cleland, et al. · European Journal of Heart Failure (2024) | TGRS Research Map | TGRS