Microfluidic-Chip-Based Formulation and In Vivo Evaluations of Squalene Oil Emulsion Adjuvants for Subunit Vaccines
These findings demonstrate a proof of concept for using microfluidic chip platforms for formulating emulsion adjuvants, offering a simpler manufacturing platform that can be deployed to low- and middle-income countries for rapid production, improving adjuvant access and aiding in pandemic preparedness.
Authors
- Shashank Bhangde
- Rushit N. Lodaya (ORCID: https://orcid.org/0000-0003-4107-3671)
- Asma Ashraf (ORCID: https://orcid.org/0000-0001-7026-670X)
- Mansoor M. Amiji
- Derek T. O’Hagan
- Stephanie Fresnay-Murray
- Tyler Garretson
Institutions
- Northeastern University (US)
- GlaxoSmithKline (United States) (US)
Publication Details
- Journal
- Vaccines
- Published
- 2024-11-28
- DOI
- https://doi.org/10.3390/vaccines12121343
- Primary Topic
- Monoclonal and Polyclonal Antibodies Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- GlaxoSmithKline