A Sustainable Catalyst‐Free Approach to Bipyrazoles Under Batch and Flow Chemistry Techniques

Abstract We have developed an efficient and sustainable approach for the synthesis of 4,4′‐bipyrazole derivatives from spirocyclopropanyl‐pyrazolone and hydrazine under mild conditions. This methodology is catalyst‐free, operating effectively in both batch and continuous flow processes. The flow synthesis allows the production of products up to 110 mg/h which provides industrial applicability and scalability. Additionally, 4,4’‐bipyraole has been transformed into a triphenyl‐substituted pyrazole derivative.