Aberrant promoter methylation, expression and function of RASSF1A gene in a series of Italian parathyroid tumors
RASSF1A and APC promoter methylation is a hallmark of parathyroid tumors; deregulation of DNMTs activity contributes to modulation of RASSF1A expression. Loss of RASSF1A may be involved in the tuning of ERK pathway in parathyroid tumors.
Authors
- Filomena Cetani
- Valentina Vaira (ORCID: https://orcid.org/0000-0003-4416-6216)
- Giulia Stefania Tavanti (ORCID: https://orcid.org/0000-0002-3951-3044)
- Vito Guarnieri (ORCID: https://orcid.org/0000-0002-5500-8558)
- Annamaria Morotti (ORCID: https://orcid.org/0000-0002-4247-4365)
- Lucia Anna Muscarella (ORCID: https://orcid.org/0000-0002-1866-8151)
- F. Perticone (ORCID: https://orcid.org/0000-0002-0010-0998)
- Sabrina Corbetta (ORCID: https://orcid.org/0000-0001-8140-3175)
- Chiara Verdelli (ORCID: https://orcid.org/0000-0002-6644-5163)
- Alfredo Scillitani (ORCID: https://orcid.org/0000-0001-9954-4187)
- Federico Pio Fabrizio (ORCID: https://orcid.org/0000-0002-9122-1348)
- Silvia Carrara (ORCID: https://orcid.org/0000-0003-4206-9463)
- Paola Maroni (ORCID: https://orcid.org/0000-0002-3444-9338)
- Riccardo Maggiore
Institutions
- University of Pisa (IT)
- University of Milan (IT)
- Università degli Studi di Enna Kore (IT)
- Casa Sollievo della Sofferenza (IT)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
- IRCCS Ospedale Galeazzi - Sant'Ambrogio (IT)
- IRCCS Ospedale San Raffaele (IT)
- IRCCS Istituto Auxologico Italiano (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- Endocrine
- Published
- 2024-11-28
- DOI
- https://doi.org/10.1007/s12020-024-04113-7
- Citations
- 1
- Primary Topic
- Genetic Syndromes and Imprinting
- Type
- article
- Field-Weighted Citation Impact
- 0.55