Diagnostic Challenges in Rhino-Orbito-Cerebral Mucormycosis With Diabetes Mellitus, Hypertensive Emergency, and Excess Alcohol Consumption

A 72-year-old male with a history of excessive alcohol intake (35+ units of alcohol daily) presented to the emergency department with bilateral vision loss, periorbital swelling, headache, and sinus congestion with bloody nasal discharge. He was newly diagnosed with diabetes mellitus and presented with severe diabetic ketoacidosis and a hypertensive emergency (blood pressure of 240/90 mmHg). Despite initial normal brain and orbital imaging, the clinical presentation was complicated by multiple life-threatening conditions and a prior immunocompetent status, thereby delaying the early suspicion of mucormycosis. This case underlines the diagnostic challenges in managing mucormycosis in a previously immunocompetent patient with overlapping critical conditions.

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Journal
Cureus
Published
2024-11-28
DOI
https://doi.org/10.7759/cureus.74663
Primary Topic
Antifungal resistance and susceptibility
Type
article
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article

Diagnostic Challenges in Rhino-Orbito-Cerebral Mucormycosis With Diabetes Mellitus, Hypertensive Emergency, and Excess Alcohol Consumption

Shahzaib Munir, Atif Awan, Hafiz Muhammad Zahid Rahim, Asma Rahim et al.
Cureus
Antifungal resistance and susceptibility
article

Diagnostic Challenges in Rhino-Orbito-Cerebral Mucormycosis With Diabetes Mellitus, Hypertensive Emergency, and Excess Alcohol Consumption

Shahzaib Munir, Atif Awan, Hafiz Muhammad Zahid Rahim, Asma Rahim, M. E. Ali Mohsin, Ayesha Hassan, Swaroopa Kinnera, Kashish Keswani Sunil, Oluwaseyi Owasoyo, Uzma Rahim
article en

Abstract

A 72-year-old male with a history of excessive alcohol intake (35+ units of alcohol daily) presented to the emergency department with bilateral vision loss, periorbital swelling, headache, and sinus congestion with bloody nasal discharge. He was newly diagnosed with diabetes mellitus and presented with severe diabetic ketoacidosis and a hypertensive emergency (blood pressure of 240/90 mmHg). Despite initial normal brain and orbital imaging, the clinical presentation was complicated by multiple life-threatening conditions and a prior immunocompetent status, thereby delaying the early suspicion of mucormycosis. This case underlines the diagnostic challenges in managing mucormycosis in a previously immunocompetent patient with overlapping critical conditions.

CureusVol. 16(11)
Withybush General Hospital (GB), Royal Stoke University Hospital (GB), Queens Hospital Center (US)
Good health and well-being
Openalex Percentile: Top 73%
Antifungal resistance and susceptibility
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Diagnostic Challenges in Rhino-Orbito-Cerebral Mucormycosis With Diabetes Mellitus, Hypertensive Emergency, and Excess Alcohol Consumption — Shahzaib Munir, Atif Awan, et al. · Cureus (2024) | TGRS Research Map | TGRS