Synthesis of 1,4‐Naphthoquinones via Palladium(II)‐Catalyzed Tertiary C−H Alkylation of Olefins Followed by C−C Bond Cleavage
Abstract An efficient method has been developed for the preparation of 1,4‐naphthoquinones via a palladium‐catalyzed reaction of 2‐aryl‐1,3‐indandiones with olefins. This reaction involves the tertiary C−H alkylation of 2‐aryl‐1,3‐indandiones with olefins to produce a tertiary alcohol, followed by C−C bond cleavage.
Authors
- Mengfan Chang
- Ting Li (ORCID: https://orcid.org/0000-0002-2186-6992)
- Wenguang Li (ORCID: https://orcid.org/0009-0003-4969-4621)
- Xu Zhang (ORCID: https://orcid.org/0000-0002-3588-3240)
- Xuefeng Xu (ORCID: https://orcid.org/0000-0003-2930-9928)
- Tongtong Ni
Institutions
- Nanyang Normal University (CN)
Publication Details
- Journal
- European Journal of Organic Chemistry
- Published
- 2024-11-28
- DOI
- https://doi.org/10.1002/ejoc.202401107
- Primary Topic
- Catalytic C–H Functionalization Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China