Prevalence of organic central precocious puberty in males: criteria for a high index of suspicion
Our findings indicate that the prevalence of pathological brain lesions in boys with CPP is considerably lower than previously reported thus making the diagnosis less alarming. Age younger than eight years, presence of neurological symptoms, family history negative for precocious puberty in first degree relatives and age of maternal menarche older than 11 years raise suspicion of organic CPP and should lead to prompt neuroimaging.
Authors
- Annalisa Deodati (ORCID: https://orcid.org/0000-0001-8636-382X)
- Valentina Pampanini (ORCID: https://orcid.org/0000-0002-8107-8015)
- Maria Elisa Amodeo (ORCID: https://orcid.org/0000-0002-8036-0430)
- Stefania Pedicelli (ORCID: https://orcid.org/0000-0003-3709-6133)
- Stefano Cianfarani (ORCID: https://orcid.org/0000-0002-2580-8781)
- Gianluca Mirra
Institutions
- University of Rome Tor Vergata (IT)
- Karolinska Institutet (SE)
- Bambino Gesù Children's Hospital (IT)
Publication Details
- Journal
- Endocrine Connections
- Published
- 2024-11-28
- DOI
- https://doi.org/10.1530/ec-24-0405
- Citations
- 2
- Primary Topic
- Ovarian cancer diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.07
Funders
- Ministero della Salute