TPM4 overexpression drives colon epithelial cell tumorigenesis by suppressing differentiation and promoting proliferation
TPM4 overexpression attenuates colon epithelial cell differentiation and promotes proliferation. Therefore, TPM4 expression may be a biomarker to enhance strategies for CRC diagnosis and treatment.
Authors
- Piotr B. Kozlowski
- Alessio Naccarati (ORCID: https://orcid.org/0000-0001-5774-0905)
- Giulio Ferrero (ORCID: https://orcid.org/0000-0002-4580-0680)
- Barbara Pardini (ORCID: https://orcid.org/0000-0001-9571-4257)
- Rajsumeet S Macwan
- Michael Papetti
Institutions
- Touro College (US)
- Department of Medical Sciences (BY)
- Candiolo Cancer Institute (IT)
- University of Turin (IT)
Publication Details
- Journal
- Neoplasia
- Published
- 2024-11-28
- DOI
- https://doi.org/10.1016/j.neo.2024.101093
- Citations
- 4
- Primary Topic
- Genetic factors in colorectal cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.70
Funders
- Associazione Italiana per la Ricerca sul Cancro