INCA033989: the first shot on goal for MPNs?
In this issue of Blood, Reis et al1 identify a monoclonal antibody, INCA033989, that selectively targets mutant calreticulin (mutCALR) in myeloproliferative neoplasms (MPNs), inhibiting its oncogenic activity without affecting normal hematopoiesis.
Authors
- Camélia Benlabiod (ORCID: https://orcid.org/0000-0001-7119-9326)
- Bethan Psaila (ORCID: https://orcid.org/0000-0001-8198-9663)
Institutions
- University of Oxford (GB)
- Oxford University Hospitals NHS Trust (GB)
Publication Details
- Journal
- Blood
- Published
- 2024-11-28
- DOI
- https://doi.org/10.1182/blood.2024026811
- Citations
- 3
- Primary Topic
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.31