INCA033989: the first shot on goal for MPNs?

In this issue of Blood, Reis et al1 identify a monoclonal antibody, INCA033989, that selectively targets mutant calreticulin (mutCALR) in myeloproliferative neoplasms (MPNs), inhibiting its oncogenic activity without affecting normal hematopoiesis.

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Publication Details

Journal
Blood
Published
2024-11-28
DOI
https://doi.org/10.1182/blood.2024026811
Citations
3
Primary Topic
Myeloproliferative Neoplasms: Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
1.31
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article

INCA033989: the first shot on goal for MPNs?

Camélia Benlabiod, Bethan Psaila
3 citations
Blood
Myeloproliferative Neoplasms: Diagnosis and Treatment
1.31
article

INCA033989: the first shot on goal for MPNs?

Camélia Benlabiod, Bethan Psaila
article en
3 citations

Abstract

In this issue of Blood, Reis et al1 identify a monoclonal antibody, INCA033989, that selectively targets mutant calreticulin (mutCALR) in myeloproliferative neoplasms (MPNs), inhibiting its oncogenic activity without affecting normal hematopoiesis.

BloodVol. 144(22)
University of Oxford (GB), Oxford University Hospitals NHS Trust (GB)
Zero hunger
Openalex Percentile: Top 17%
Myeloproliferative Neoplasms: Diagnosis and Treatment
1.31
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INCA033989: the first shot on goal for MPNs? — Camélia Benlabiod, Bethan Psaila · Blood (2024) | TGRS Research Map | TGRS