Short Communication: Analysis of the Spectrum of Glomerular Diseases in Chronic Filariasis Diagnosed in a Tertiary Care Hospital in India

<b><i>Introduction:</i></b> The study presents renal manifestations in chronic filariasis, a substantial health concern in the eastern and north-eastern regions of India. <b><i>Materials and Methods:</i></b> The study is a retrospective analysis of a renal biopsy series of patients with chronic filariasis from a tertiary care hospital in Odisha. It involves eight cases of chronic filariasis. <b><i>Results:</i></b> Common indications of biopsy were nephrotic syndrome, chyluria, and unexplained renal failure. The mean duration from the diagnosis of filariasis to the onset of glomerular diseases was 15.75 years, SD ± 4.2 years. Patients were followed up for a minimum of 6 months. Renal histopathology revealed various patterns, including membranous nephropathy, minimal change disease, IGA nephropathy, and membranoproliferative glomerulonephritis. <b><i>Conclusion:</i></b> The study fills a critical gap in the literature by elucidating renal biopsy findings in chronic filariasis. The multifaceted nature of this disease underscores the need for continued research to understand kidney diseases due to filariasis, especially in endemic regions.

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Journal
Vector-Borne and Zoonotic Diseases
Published
2024-11-28
DOI
https://doi.org/10.1089/vbz.2024.0038
Primary Topic
Parasitic Diseases Research and Treatment
Type
article
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article

Short Communication: Analysis of the Spectrum of Glomerular Diseases in Chronic Filariasis Diagnosed in a Tertiary Care Hospital in India

Pavithra Ayyanar, Suvendu Purkait, Priti Meena, Anish Garg et al.
Vector-Borne and Zoonotic Diseases
Parasitic Diseases Research and Treatment
article

Short Communication: Analysis of the Spectrum of Glomerular Diseases in Chronic Filariasis Diagnosed in a Tertiary Care Hospital in India

Pavithra Ayyanar, Suvendu Purkait, Priti Meena, Anish Garg, Paromita Das, Sandip Panda
article en

Abstract

<b><i>Introduction:</i></b> The study presents renal manifestations in chronic filariasis, a substantial health concern in the eastern and north-eastern regions of India. <b><i>Materials and Methods:</i></b> The study is a retrospective analysis of a renal biopsy series of patients with chronic filariasis from a tertiary care hospital in Odisha. It involves eight cases of chronic filariasis. <b><i>Results:</i></b> Common indications of biopsy were nephrotic syndrome, chyluria, and unexplained renal failure. The mean duration from the diagnosis of filariasis to the onset of glomerular diseases was 15.75 years, SD ± 4.2 years. Patients were followed up for a minimum of 6 months. Renal histopathology revealed various patterns, including membranous nephropathy, minimal change disease, IGA nephropathy, and membranoproliferative glomerulonephritis. <b><i>Conclusion:</i></b> The study fills a critical gap in the literature by elucidating renal biopsy findings in chronic filariasis. The multifaceted nature of this disease underscores the need for continued research to understand kidney diseases due to filariasis, especially in endemic regions.

Vector-Borne and Zoonotic DiseasesVol. 25(3)
All India Institute of Medical Sciences Bhubaneswar (IN)
Openalex Percentile: Top 73%
Parasitic Diseases Research and Treatment
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