Delivery of IL-12 by neoantigen-reactive T cells promotes antitumor immunity in murine osteosarcoma mode
Our study presents a novel and efficacious strategy for osteosarcoma immunotherapy by harnessing NRT cells as targeted cytokine delivery vehicles.
Authors
- Qingyu Chen (ORCID: https://orcid.org/0000-0002-6036-1516)
- Meixiang Zhou (ORCID: https://orcid.org/0000-0002-0305-4878)
- Daliu Min (ORCID: https://orcid.org/0000-0001-9589-4032)
- Kun Han (ORCID: https://orcid.org/0000-0001-9272-5567)
- Yan Huang (ORCID: https://orcid.org/0000-0003-4314-7267)
- Xingxing Sun (ORCID: https://orcid.org/0000-0002-7301-9250)
- Hongling Zhu (ORCID: https://orcid.org/0000-0002-0695-2569)
- Cong Tian
Institutions
- Tongji University (CN)
- Shanghai Jiao Tong University (CN)
- Shanghai Tenth People's Hospital (CN)
- Shanghai Sixth People's Hospital (CN)
Publication Details
- Journal
- Immunotherapy Advances
- Published
- 2024-11-28
- DOI
- https://doi.org/10.1093/immadv/ltae010
- Citations
- 3
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.85