Roles of Cancer Histology Type and HPV Genotype in HPV ctDNA Detection at Baseline in Cervical Cancer: Implications for Tumor Burden Assessment
This study found the impact of histology and HPV genotype on HPV ctDNA at baseline in cervical cancer. HPV18 and adenocarcinoma were associated with a higher baseline HPV ctDNA detection rate. These results suggest the need for different HPV ctDNA approaches for analyzing tumor burden. This finding may also serve as a useful reference for posttreatment surveillance studies.
Authors
- Sung Jong Lee (ORCID: https://orcid.org/0000-0002-6077-2649)
- Sook Hee Hong (ORCID: https://orcid.org/0000-0003-4299-5694)
- Keun Ho Lee (ORCID: https://orcid.org/0000-0001-9005-7796)
- Miseon Lee (ORCID: https://orcid.org/0000-0001-9394-2643)
- Hee Seung Kim (ORCID: https://orcid.org/0000-0003-1238-7604)
- Eun Ji Lee (ORCID: https://orcid.org/0000-0002-4362-939X)
- Ah-Won Lee
- Jun Kang (ORCID: https://orcid.org/0009-0006-5025-1053)
Institutions
- Seoul National University (KR)
- St. Mary's Hospital (US)
- The Catholic University of Korea Seoul St. Mary's Hospital (KR)
- Chung-Ang University (KR)
- Catholic University of Korea (KR)
Publication Details
- Journal
- Pathobiology
- Published
- 2024-11-27
- DOI
- https://doi.org/10.1159/000542638
- Citations
- 3
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 1.16