Double Trouble in the Basement! A Case of PLA2R-Associated Membranous Nephropathy with Atypical Anti-Glomerular Basement Membrane Disease

For our patient, rituximab resulted in remission of proteinuria. The lack of temporal association with the malignancy is consistent with the biopsy findings of PLA2R-associated membranous nephropathy. While there is not an established guideline for atypical anti-GBM disease, our case demonstrates the utility of rituximab for the management of concurrent atypical anti-GBM disease with membranous nephropathy.

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Publication Details

Journal
Glomerular Diseases
Published
2024-11-27
DOI
https://doi.org/10.1159/000542859
Primary Topic
Renal Diseases and Glomerulopathies
Type
article
Field-Weighted Citation Impact
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article

Double Trouble in the Basement! A Case of PLA2R-Associated Membranous Nephropathy with Atypical Anti-Glomerular Basement Membrane Disease

Ziad M. El‐Zaatari, Ali R. Khan, Theresa Thurston, Renuka Tolani et al.
Glomerular Diseases
Renal Diseases and Glomerulopathies
article

Double Trouble in the Basement! A Case of PLA2R-Associated Membranous Nephropathy with Atypical Anti-Glomerular Basement Membrane Disease

Ziad M. El‐Zaatari, Ali R. Khan, Theresa Thurston, Renuka Tolani, Angelina Edwards, Shane A. Bobart, Steffi Sathiyaraj, Luan D. Truong, David Lyu
article en

Abstract

For our patient, rituximab resulted in remission of proteinuria. The lack of temporal association with the malignancy is consistent with the biopsy findings of PLA2R-associated membranous nephropathy. While there is not an established guideline for atypical anti-GBM disease, our case demonstrates the utility of rituximab for the management of concurrent atypical anti-GBM disease with membranous nephropathy.

Glomerular DiseasesVol. 5(1)
Cornell University (US), Methodist Hospital (US), Methodist Hospital (US), University of Houston (US), Texas A&M University (US)
Good health and well-being
Openalex Percentile: Top 69%
Renal Diseases and Glomerulopathies
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