An electrochemical biosensor for the detection of tuberculosis specific DNA with CRISPR-Cas12a and redox-probe modified oligonucleotide
This is the first study reporting the CRISPR-Cas12a-based electrochemical sensor for TB. The developed CRISPR-Cas12a endonuclease-based electrochemical biosensor provides a potentially powerful platform for the accurate detection of <i>Mycobacterium tuberculosis</i>.
Authors
- Madoka Nagata (ORCID: https://orcid.org/0009-0002-7336-2929)
- Koji Sode (ORCID: https://orcid.org/0000-0002-9833-2091)
- Shah Rukh Abbas
- Saman Taufiq
Institutions
- University of North Carolina at Chapel Hill (US)
- National University of Sciences and Technology (PK)
Publication Details
- Journal
- Heliyon
- Published
- 2024-11-28
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e40754
- Citations
- 11
- Primary Topic
- CRISPR and Genetic Engineering
- Type
- article
- Field-Weighted Citation Impact
- 2.57
Funders
- North Carolina State University
- Higher Education Commission, Pakistan
- Higher Education Commision, Pakistan
- University of North Carolina at Chapel Hill