Advanced Neuroimaging and Clinical Findings in a Case of Linear Scleroderma En Coup De Sabre Presenting With Seizures

Scleroderma is a rare connective tissue disease categorized as systemic or localized. Linear subtype of localized scleroderma usually manifests as a cutaneous linear scar-like lesion most commonly on the scalp. It may present with neurologic, ophthalmologic, and rheumatologic symptoms. We present a case of a 24-year-old female patient with a band-like scalp brown sclerotic lesion in the left upper frontal region presenting with headaches and a first-time seizure who underwent 3.0-T magnetic resonance and described the structural and advanced neuroimaging findings, including perfusion and spectroscopy, that may help narrow differential diagnosis of linear scleroderma.