Anti-allodynic effect of intrathecal antibodies against macrophage-inducible C-type lectin in spinal nerve ligation model in rat
The current study demonstrates the anti-allodynic effect of Mincle antibodies and additive interaction with TLR4 inhibition in spinal nerve ligation model, suggesting the potential of blocking of Mincle signaling with its antibodies as a novel treatment strategy for neuropathic pain.
Authors
- Dong Ho Kang (ORCID: https://orcid.org/0000-0002-5299-6861)
- Jeong Il Choi (ORCID: https://orcid.org/0000-0002-3571-2599)
- Jihoon Yang (ORCID: https://orcid.org/0000-0002-0300-7705)
- Woong Mo Kim
- Hong Beom Bae
Institutions
- Chonnam National University Hospital (KR)
Publication Details
- Journal
- Heliyon
- Published
- 2024-11-28
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e40694
- Citations
- 1
- Primary Topic
- Pain Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.33
Funders
- National Research Foundation
- Korea Health Industry Development Institute
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea