CB2R activation enhances tumor-associated macrophages-mediated phagocytosis of glioma cell
Overall, our findings show that CB2R activation promotes TAMs-mediated phagocytosis of tumor cells by enhancing CD36 expression, implying that JWH133 could be a useful therapeutic approach to improving chemotherapeutic efficacy against GBM.
Authors
- Siyuan Lu (ORCID: https://orcid.org/0000-0001-6720-1323)
- Xuezhu Chen
- Yang Yang (ORCID: https://orcid.org/0000-0001-6472-5578)
- Junlong Li (ORCID: https://orcid.org/0000-0003-1118-6245)
Institutions
- Jiangsu University (CN)
- Army Medical University (CN)
- Affiliated Hospital of Jiangsu University (CN)
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Southwest Hospital (CN)
- Chongqing Public Health Medical Center (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Heliyon
- Published
- 2024-11-28
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e40806
- Citations
- 4
- Primary Topic
- Phagocytosis and Immune Regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.96
Funders
- China Postdoctoral Science Foundation
- Natural Science Foundation of Chongqing
- Centre Scientifique et Technique du Bâtiment
- Postdoctoral Research Foundation of China
- National Postdoctoral Program for Innovative Talents