Apalutamide in Metastatic Castration-sensitive Prostate Cancer: Results from the Multicenter Real-world ARON-3 Study
The ARON-3 project collects data for patients with prostate cancer treated in multiple centers worldwide to assess outcomes in the real-world setting. We analyzed data for patients with metastatic hormone-sensitive prostate cancer receiving apalutamide. Our results show that apalutamide is a safe and effective drug in the real-world setting as well as in clinical trials.
Authors
- Tarek Taha (ORCID: https://orcid.org/0000-0001-7936-5245)
- Ondřej Fiala (ORCID: https://orcid.org/0000-0002-4096-7385)
- Zin Myint (ORCID: https://orcid.org/0000-0002-3479-4203)
- Pasquale Rescigno (ORCID: https://orcid.org/0000-0002-4668-4765)
- Sebastiano Buti (ORCID: https://orcid.org/0000-0003-0876-0226)
- Camillo Porta (ORCID: https://orcid.org/0000-0003-2412-1563)
- Rossana Berardi (ORCID: https://orcid.org/0000-0002-9529-2960)
- Matteo Santoni (ORCID: https://orcid.org/0000-0001-7340-6173)
- E Thomas Pierce
- Thomas Büttner (ORCID: https://orcid.org/0000-0003-0316-9621)
- Orazio Caffo
- Michal Uher (ORCID: https://orcid.org/0000-0001-8970-5928)
- Luca Galli (ORCID: https://orcid.org/0000-0001-6008-0266)
- Carlo Messina
- Renato Bisonni (ORCID: https://orcid.org/0000-0003-1707-2679)
- Andrey Soares (ORCID: https://orcid.org/0000-0003-4980-6729)
- Veronica Mollica (ORCID: https://orcid.org/0000-0002-5169-3631)
- Giandomenico Roviello (ORCID: https://orcid.org/0000-0001-5504-8237)
- Ray Kopp Manneh
- Nicola Battelli
- Mimma Rizzo (ORCID: https://orcid.org/0000-0001-7743-741X)
- Aristotelis Bamias (ORCID: https://orcid.org/0000-0002-5996-7262)
- Luigi Formisano (ORCID: https://orcid.org/0000-0001-7205-5105)
- Marc Matrana (ORCID: https://orcid.org/0000-0002-7301-170X)
- Franco Morelli (ORCID: https://orcid.org/0000-0003-2378-9094)
- Nicolò Cavasin
- Lorena Incorvaia (ORCID: https://orcid.org/0000-0002-1199-7286)
- Francesco Massari (ORCID: https://orcid.org/0000-0001-6476-6871)
- Gaetano Aurilio (ORCID: https://orcid.org/0000-0002-5632-6427)
- Gaetano Facchini (ORCID: https://orcid.org/0000-0002-7430-001X)
- Alexandr Poprach (ORCID: https://orcid.org/0000-0003-4698-9195)
- Fernando Sabino Marques Monteiro (ORCID: https://orcid.org/0000-0002-6621-8251)
- Sarah Scagliarini (ORCID: https://orcid.org/0000-0001-5814-2296)
- Francesca Zacchi (ORCID: https://orcid.org/0000-0002-7448-7822)
- Francesco Grillone (ORCID: https://orcid.org/0009-0009-6010-7604)
- Xue Jiang (ORCID: https://orcid.org/0000-0002-2518-3355)
- Umberto Basso (ORCID: https://orcid.org/0000-0002-5075-2177)
- Roubini Zakopoulou
- Jawaher Ansari (ORCID: https://orcid.org/0000-0001-5525-548X)
- Daniele Santini (ORCID: https://orcid.org/0000-0002-9118-3337)
- Jiří Navrátil (ORCID: https://orcid.org/0000-0001-6717-1259)
- Alessandro Rizzo (ORCID: https://orcid.org/0000-0002-6085-648X)
- Fernando Cotait Maluf (ORCID: https://orcid.org/0000-0002-4288-9018)
- Gianpaolo Spinelli
- R. Chandler
- Fabio Calabrò
Institutions
- University of Verona (IT)
- University of Parma (IT)
- Royal Marsden NHS Foundation Trust (GB)
- National and Kapodistrian University of Athens (GR)
- Charles University (CZ)
- University Hospital Bonn (DE)
- Ochsner Medical Center (US)
- Casa Sollievo della Sofferenza (IT)
- Hospital Israelita Albert Einstein (BR)
- Policlinico Umberto I (IT)
- Freeman Hospital (GB)
- Markey Cancer Center (US)
- Popular University of Cesar (CO)
- Eastern Cooperative Oncology Group (US)
- Tawam Hospital (AE)
- Ospedale Santa Chiara (IT)
- Veterinary Oncological Center (IT)
- Azienda Universitaria Ospedaliera Consorziale - Policlinico Bari (IT)
- Istituto Oncologico Veneto (IT)
- Beneficência Portuguesa de São Paulo (BR)
- Masaryk Memorial Cancer Institute (CZ)
- Ospedale Santa Maria (IT)
- Federico II University Hospital (IT)
- Azienda USL di Bologna (IT)
- Istituto Tumori Bari (IT)
- Azienda di Rilievo Nazionale ed Alta Specializzazione (IT)
- Azienda Ospedaliera Pugliese Ciaccio (IT)
- Hospital Sírio-Libanês (BR)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Azienda Ospedaliera Universitaria Pisana (IT)
- Ospedale di Macerata
- University of Florence (IT)
- University of Macerata (IT)
- University of Bari Aldo Moro (IT)
- European Institute of Oncology (IT)
- Newcastle University (GB)
- University of Palermo (IT)
- University of Bologna (IT)
Publication Details
- Journal
- European Urology Oncology
- Published
- 2024-11-29
- DOI
- https://doi.org/10.1016/j.euo.2024.11.005
- Citations
- 11
- Primary Topic
- Prostate Cancer Treatment and Research
- Type
- article
- Field-Weighted Citation Impact
- 4.61