LncRNA H19 promotes osteoclast differentiation by sponging miR-29c-3p to increase expression of cathepsin K
H19 upregulates cathepsin K expression through sponging miR-29c-3p, which promoting osteoclast differentiation and enhancing bone resorption. This underscores the potential of H19 and miR-29c-3p as promising biomarkers for osteoporosis.
Authors
- Cuiying Li (ORCID: https://orcid.org/0000-0002-5536-5432)
- Anqi Tao
- Huazhi Li
- Xinxin Zhan
- Hongyi Tang
- Tong Wu (ORCID: https://orcid.org/0000-0002-0842-5623)
- Xinyu Cui (ORCID: https://orcid.org/0000-0002-0539-5350)
- Zeyun Ma
- Zheng Fu (ORCID: https://orcid.org/0009-0000-5974-7617)
- Jiuhui Jiang (ORCID: https://orcid.org/0000-0003-4881-5949)
- Yi-Xiang Wang (ORCID: https://orcid.org/0000-0002-4021-4228)
Institutions
- King University (US)
- Peking University (CN)
- Aerospace Center Hospital (CN)
- Stomatology Hospital (CN)
- Peking University Third Hospital (CN)
- Beijing Haidian Hospital (CN)
Publication Details
- Journal
- Bone
- Published
- 2024-11-29
- DOI
- https://doi.org/10.1016/j.bone.2024.117340
- Citations
- 4
- Primary Topic
- Bone Metabolism and Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.94