IRF4 regulates myeloid-derived suppressor cells expansion and function in Schistosoma japonicum-infected mice
Overall, these findings highlight the importance of IRF4 in regulating MDSCs and their impact on tissue damage during S. japonicum infection, providing valuable insights into potential therapeutic targets for managing the pathological consequences of this parasitic infection.
Authors
- Zhihan Jiang (ORCID: https://orcid.org/0000-0001-5270-9351)
- Lengshan Mo
- Tengfei Hu (ORCID: https://orcid.org/0000-0001-9033-5493)
- Yanwei Qi (ORCID: https://orcid.org/0000-0001-8899-2056)
- Quan Yang (ORCID: https://orcid.org/0000-0002-2778-6862)
- Guorong Deng (ORCID: https://orcid.org/0000-0001-7095-3331)
- Lu Zhou (ORCID: https://orcid.org/0000-0002-0424-7348)
- Jian Zhang (ORCID: https://orcid.org/0000-0003-3373-9621)
- Qingqing Li (ORCID: https://orcid.org/0000-0002-3166-3195)
- Yiqiang Zhu
- Yi Zhao (ORCID: https://orcid.org/0000-0001-5602-6048)
- Qingping Wu (ORCID: https://orcid.org/0000-0001-6503-359X)
- Peibin Lin
- Cansheng Hong
Institutions
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- State Key Laboratory of Respiratory Disease (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Parasites & Vectors
- Published
- 2024-11-28
- DOI
- https://doi.org/10.1186/s13071-024-06543-8
- Citations
- 1
- Primary Topic
- Parasites and Host Interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.52
Funders
- Guangzhou Medical University
- National Natural Science Foundation of China
- National Key Research and Development Program of China