Lack of Lloviu Virus Disease Development in Ferret Model
The first isolate of the emerging filovirus Lloviu virus (LLOV) was obtained in 2022. No animal disease models have been established. We assessed the pathogenic potential of LLOV in ferrets after intranasal, intramuscular, or aerosol exposure. The lack of disease development shows ferrets are not a disease model for LLOV.
Authors
- Kyle L. O’Donnell
- Ayato Takada (ORCID: https://orcid.org/0000-0003-2464-6642)
- Atsushi Okumura (ORCID: https://orcid.org/0000-0002-7779-3059)
- Chad S. Clancy (ORCID: https://orcid.org/0000-0002-5354-9270)
- Gábor Kemenesi (ORCID: https://orcid.org/0000-0001-9775-3065)
- Andrea Marzi (ORCID: https://orcid.org/0000-0003-0186-9587)
- Paige Fletcher (ORCID: https://orcid.org/0000-0001-6860-305X)
- Joseph F. Rhoderick
- Trenton Bushmaker (ORCID: https://orcid.org/0000-0002-2161-4808)
- Corey W. Henderson
Publication Details
- Journal
- Emerging infectious diseases
- Published
- 2024-11-29
- DOI
- https://doi.org/10.3201/eid3012.240818
- Citations
- 4
- Primary Topic
- Viral Infections and Outbreaks Research
- Type
- article
- Field-Weighted Citation Impact
- 1.56
Funders
- Magyar Tudományos Akadémia
- National Institutes of Health
- National Institute of Allergy and Infectious Diseases