Upregulation of LncRNA WT1-AS Inhibits Tumor Growth and Promotes Autophagy in Gastric Cancer via Suppression of PI3K/Akt/mTOR Pathway
The upregulation of lncRNA WT1-AS could suppress the PI3K/Akt/mTOR pathway, which inhibits cell migration and cell cycle arrest while promoting autophagy in gastric cancer cells.
Authors
- Guiyuan Jin (ORCID: https://orcid.org/0000-0003-4629-5505)
- Jian Huang
- Jilan Liu
- Xiaobei Zhang (ORCID: https://orcid.org/0000-0002-9228-8720)
- Yonghong Yang (ORCID: https://orcid.org/0000-0001-9083-2801)
- Shiqi Liu (ORCID: https://orcid.org/0000-0001-9070-6493)
- Jin Meng (ORCID: https://orcid.org/0000-0003-2611-5407)
- Xiaoying Yao (ORCID: https://orcid.org/0000-0001-6087-7996)
- Zhang Bao-gui (ORCID: https://orcid.org/0000-0003-3169-0676)
Institutions
- Affiliated Hospital of Jining Medical University (CN)
Publication Details
- Journal
- Current Molecular Pharmacology
- Published
- 2024-11-08
- DOI
- https://doi.org/10.2174/0118761429318398240918063450
- Citations
- 27
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 7.70
Funders
- National Natural Science Foundation of China
- Jining Medical University
- Health and Family Planning Commission of Shandong Province