Synthesis of <i>N</i>-Heteroaryl <i>C</i>-Glycosides and Polyhydroxylated Alkanes with Diaryl Groups from Unprotected Sugars
HCl-catalyzed <i>C</i>-glycosylation was described herein for the convenient preparation of <i>N</i>-heteroaryl <i>C</i>-glycosides and polyhydroxylated alkanes with diaryl groups using hetereoaryl amines and unprotected sugars as starting materials. The reaction temperature and the amounts of aryl amines and HCl had significant effects on reactions. The method provided a highly efficient and environmentally friendly route for constructing <i>C</i>-glycosides at low cost.
Authors
- Jilai Wu (ORCID: https://orcid.org/0000-0002-8236-0709)
- Likai Zhou
- Chao Wei (ORCID: https://orcid.org/0000-0002-7425-5132)
- Hua Chen (ORCID: https://orcid.org/0000-0001-5564-4610)
- Yixuan Liu (ORCID: https://orcid.org/0000-0001-5046-7379)
Institutions
- Hebei University (CN)
- Xingtai University (CN)
Publication Details
- Journal
- ACS Omega
- Published
- 2024-11-27
- DOI
- https://doi.org/10.1021/acsomega.4c07671
- Citations
- 3
- Primary Topic
- Carbohydrate Chemistry and Synthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.75
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hebei Province
- Baoding City Science and Technology and Intellectual Property Bureau