Coronary microvascular function and atherosclerotic plaque burden in ischaemia and no obstructive coronary arteries: a secondary analysis of the CorMicA trial
Reduced CFR, MRR and RRR, and MVA were associated with increased coronary atherosclerotic plaque burden, as evidenced by higher Gensini scores. These novel findings provide a mechanistic link between INOCA and cardiovascular events, reinforcing the importance of antiatherosclerosis therapy in patients with MVA.
Authors
- Anna Kamdar (ORCID: https://orcid.org/0000-0001-9194-547X)
- Richard Good (ORCID: https://orcid.org/0000-0002-3906-1025)
- Daniel Ang (ORCID: https://orcid.org/0000-0002-1189-4500)
- Novalia Sidik (ORCID: https://orcid.org/0000-0002-7620-2640)
- Margaret McEntegart (ORCID: https://orcid.org/0000-0001-5135-3322)
- J. Paul Rocchiccioli (ORCID: https://orcid.org/0000-0003-1350-1544)
- Keith Robertson
- Robert Sykes (ORCID: https://orcid.org/0000-0003-1010-5474)
- Hany Eteiba (ORCID: https://orcid.org/0000-0003-2200-8567)
- Colin Berry (ORCID: https://orcid.org/0000-0002-4547-8636)
- Damien Collison (ORCID: https://orcid.org/0000-0002-3531-0872)
- Mitchell Lindsay (ORCID: https://orcid.org/0000-0002-4654-712X)
- Stuart Hood (ORCID: https://orcid.org/0000-0003-4708-3926)
- Alex McConnachie (ORCID: https://orcid.org/0000-0002-7262-7000)
- Thomas J. Ford (ORCID: https://orcid.org/0000-0003-4009-6652)
- Jaclyn Carberry (ORCID: https://orcid.org/0000-0002-4184-0714)
- Peter McCartney (ORCID: https://orcid.org/0000-0001-7482-1811)
- Aadil Shaukat (ORCID: https://orcid.org/0000-0001-7409-6859)
- Keith G Oldroyd
- Stuart Watkins
- David Carrick
- Ross McGeoch
Institutions
- Golden Jubilee National Hospital (GB)
- Hairmyres Hospital (GB)
- Central Coast Local Health District (AU)
- Columbia University (US)
- University of Glasgow (GB)
Publication Details
- Journal
- Heart
- Published
- 2024-11-27
- DOI
- https://doi.org/10.1136/heartjnl-2024-324677
- Citations
- 7
- Primary Topic
- Cardiac Imaging and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 2.83
Funders
- AstraZeneca
- Boston Scientific Corporation
- British Heart Foundation
- Biosensors International Group
- Medical Research Council
- Engineering and Physical Sciences Research Council
- Daiichi Sankyo Europe